Incorporating single-arm studies in meta-analysis of randomised controlled trials: a simulation study.
Janharpreet SinghKeith R AbramsSylwia BujkiewiczPublished in: BMC medical research methodology (2021)
The hierarchical power and commensurate prior methods provide the most robust approach to synthesising aggregate data from RCTs and single-arm studies, balancing the need to account for bias and differences in between-study heterogeneity, whilst reducing uncertainty in estimates. This work was restricted to considering a pairwise meta-analysis using aggregate data.