Are hospitalized patients with inflammatory bowel disease at increased risk of invasive bacterial infections? Results from POLIBD 3-year cohort study.
Jolanta GruszeckaRafał FilipPublished in: Gut pathogens (2021)
The aim of this study was to determine the dominant species of bacteria found in blood cultures collected from patients under treatment in the tertiary inflammatory bowel disease (IBD) center in Poland. The dominant pathogen isolated from blood in patients with IBD was Staphylococcus epidermidis MRCNS (MRCNS-methicillin-resistant coagulase-negative Staphylococcus), a strain resistant to all beta-lactam antibiotics (penicillins, penicillins with B-lactamase inhibitor, cephalosporins and carbapenems). The second most commonly isolated pathogen found in the blood samples was Escherichia coli. Blood cultures were found to be positive for these pathogens more frequently in male patients (90.0%). An increased risk of bacteremia in IBD patients was associated with prolonged hospitalization.
Keyphrases
- escherichia coli
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- staphylococcus aureus
- prognostic factors
- gram negative
- multidrug resistant
- patients with inflammatory bowel disease
- patient reported outcomes
- antimicrobial resistance
- combination therapy
- methicillin resistant staphylococcus aureus
- replacement therapy