Pilot study of a combined genomic and epidemiologic surveillance program for hospital-acquired multidrug-resistant pathogens across multiple hospital networks in Australia.

Norelle L SherryRobyn S LeeClaire L GorrieJason C KwongRhonda L StuartTony M KormanCaroline MarshallCharlie HiggsHiu Tat ChanMaryza GrahamPaul D R JohnsonMarcel J LeroiCaroline ReedMichael J RichardsMonica A SlavinLeon J WorthBenjamin P HowdenM Lindsay Graysonnull null

Published in: Infection control and hospital epidemiology (2020)

Genomic and epidemiologic data from multiple institutions can feasibly be combined prospectively, providing substantial insights into the burden and distribution of MDROs, including in-hospital transmission. This analysis enables infection control teams to target interventions more effectively.

Keyphrases

multidrug resistant
healthcare
acute care
gram negative
adverse drug
copy number
public health
emergency department
electronic health record
machine learning
quality improvement
acinetobacter baumannii
gene expression
escherichia coli
cystic fibrosis
dna methylation
klebsiella pneumoniae
genome wide
data analysis