A unique case of miliary pulmonary tuberculosis induced by bacillus Calmette-Guérin intravesical instillation with COVID-19 superinfection.
Nicolò BrandiLaura BartalenaCristina MosconiRita GolfieriPublished in: SA journal of radiology (2021)
Intravesical instillation of Bacillus Calmette-Guérin (BCG) is used as an adjuvant treatment of bladder cancer. Systemic BCG infection occurs in less than 1% of cases, and pulmonary involvement is even rarer (0.3% - 0.7%), with a favourable prognosis. A 78-year-old male developed miliary tuberculosis (TB) secondary to intravesical BCG treatment and subsequent coronavirus disease 2019 (COVID-19) superinfection that led to patient death. High awareness amongst clinicians is needed to proceed with immediate appropriate therapy in these patients, especially during the COVID-19 pandemic.
Keyphrases
- coronavirus disease
- muscle invasive bladder cancer
- pulmonary tuberculosis
- mycobacterium tuberculosis
- sars cov
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- early stage
- stem cells
- emergency department
- mesenchymal stem cells
- peritoneal dialysis
- patient reported outcomes
- electronic health record