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Identifying risk factors for the development of sepsis during adult severe malaria.

Tsi NjimArjen DondorpMavuto MukakaEric O Ohuma
Published in: Malaria journal (2018)
The proposed model identifies patients with severe malaria at risk of developing clinical sepsis, potentially benefiting from antibiotic treatment in addition to anti-malarials. The model will need further evaluation with more strictly defined bacterial sepsis as outcome measure.
Keyphrases
  • septic shock
  • acute kidney injury
  • intensive care unit
  • plasmodium falciparum
  • early onset
  • genome wide
  • gene expression
  • dna methylation
  • drug induced
  • combination therapy
  • replacement therapy
  • childhood cancer