A Comprehensive Review of Vagus Nerve Stimulation for Depression.

Christopher W AustelleGeorgia H O'LearySean ThompsonElise GruberAlex KahnAndrew J ManettBaron ShortBashar W Badran

Published in: Neuromodulation : journal of the International Neuromodulation Society (2021)

The mood effects of VNS were discovered from clinical trials investigating the use of VNS for reducing seizures in epileptic patients. Since then, VNS has gone on to be FDA approved for depression. The field of VNS is growing, and as noninvasive VNS quickly advances, it is important to consider a historical perspective to develop future brain stimulation therapies.

Keyphrases

clinical trial
end stage renal disease
sleep quality
depressive symptoms
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
bipolar disorder
current status
resting state
patient reported outcomes
cerebral ischemia
double blind