Synthesis of carbohydrate building blocks via regioselective uniform protection/deprotection strategies.
Tinghua WangAlexei V DemchenkoPublished in: Organic & biomolecular chemistry (2019)
Discussed herein is the synthesis of partially protected carbohydrates by manipulating only one type of a protecting group for a given substrate. The first focus of this review is the uniform protection of an unprotected starting material in a way that only one (or two) hydroxyl group remains unprotected. The second focus involves regioselective partial deprotection of uniformly protected compounds in a way that only one (or two) hydroxyl group becomes liberated.
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