Human Immunodeficiency Virus Is Associated With Higher Levels of Systemic Inflammation Among Kenyan Adults Despite Viral Suppression.

Sarah J MasyukoStephanie T PageStephen J PolyakJohn KinuthiaAlfred O OsotiFredrick C OtienoJoseph M KibachioJerusha N MogakaPaul M MachariaBhavna H ChohanJessica WognerAidan O'ConnorTecla M TemuJerry S ZifodyaAmos OtedoDamalie NakanjakoJames P HughesCarey Farquhar

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)

We found higher levels of systemic inflammatory biomarkers among PLHIV who were virally suppressed, and this was independent of traditional CVD risk factors. Further longitudinal analyses to determine whether these inflammatory markers predict future CVD events, and are possible therapeutic targets among PLHIV, are warranted.

Keyphrases

human immunodeficiency virus
risk factors
hepatitis c virus
antiretroviral therapy
hiv infected
sars cov
oxidative stress
current status
hiv positive