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ESI MS for Microsized Bioparticles.

Abdil OzdemirJung-Lee LinMustafa GulfenSzu-Hsueh LaiChun-Jen HsiaoNelson G ChenChung-Hsuan Chen
Published in: Analytical chemistry (2017)
An ESI ion trap mass spectrometer was designed for high-throughput and rapid mass analysis of large bioparticles. Mass calibration of the instrument was performed using commercially available polystyrene (PS) microparticles with a size comparable to cancer cells. Different sizes of MCF-7 breast cancer cells (8 to 15 μm) were used in this study. The masses of different cancer cells were measured. This system allows for the analysis of all types of particles.
Keyphrases
  • ms ms
  • breast cancer cells
  • high throughput
  • mass spectrometry
  • multiple sclerosis
  • high resolution
  • single cell
  • magnetic resonance
  • computed tomography
  • contrast enhanced
  • ultrasound guided
  • quantum dots