The ABCG8 polymorphism increases the risk of gallbladder cancer in the general population and gallstones in obese patients from Poland.
Lukasz KrupaPiotr KalinowskiJoanna LigockaMarc DauerKrzysztof JankowskiJolanta GozdowskaBeata KrukPiotr MilkiewiczKrzysztof ZieniewiczMarek KrawczykSusanne N WeberFrank LammertMarcin KrawczykPublished in: European journal of clinical investigation (2024)
The ABCG8 p.D19H common risk variant increases the risk of developing gallbladder cancer in Central Europeans and enhances the risk of gallstones in the obese. Carriers of the p.D19H variant might benefit from personalized preventive strategies, particularly regarding gallbladder cancer.