Early Alteration of Right Ventricle-Pulmonary Artery Coupling in Experimental Heart Failure With Preserved Ejection Fraction.

Géraldine HubeschCéline DewachterLaura ChometteEmeline HupkensPascale JespersGrégory VeghMathilde DopplerUmair Sheikh MohammadAnaïs ThiriardMyriam RemmelinkJean-Luc VachiéryKathleen McEnteeLaurence Dewachter

Published in: Journal of the American Heart Association (2024)

Obesity-associated HFpEF in rats spontaneously evolves to pulmonary hypertension-HFpEF associated with impaired right ventricle-pulmonary artery coupling that appears disproportionate to a slight increase in RV afterload.

Keyphrases

pulmonary artery
pulmonary hypertension
pulmonary arterial hypertension
room temperature
coronary artery
mycobacterium tuberculosis
metabolic syndrome
insulin resistance
weight loss
type diabetes
weight gain
high fat diet induced
physical activity
adipose tissue