Emotional symptoms and cognitive function outcomes of subthalamic stimulation in Parkinson's disease depend on location of active contacts and the volume of tissue activated.

Kun LiangRen-Peng LiYuan GaoChong LiuQiao WangDong-Mei GaoHui-Min WangLiang-Ying ZouXin ZhangChun-Lei HanJian-Guo Zhang Fan-Gang Meng

Published in: CNS neuroscience & therapeutics (2023)

Our results provide evidence that the 12-month outcomes of cognitive function and emotional symptoms in PD patients with STN-DBS were closely related to the specific location of the active contacts in the STN and influenced by the VTA.

Keyphrases

deep brain stimulation
parkinson disease
metabolic syndrome
sleep quality
glycemic control
insulin resistance
depressive symptoms
physical activity