Post-hematopoietic stem cell transplantation relapse: Role of checkpoint inhibitors.
Elham RoshandelFarzaneh TavakoliSayeh ParkhidehSedigheh Sadat AkhlaghiMaria Tavakoli ArdakaniMasoud SoleimaniPublished in: Health science reports (2022)
Here we provided a mini-review discussing the experiences of three immune checkpoints, including nivolumab, pembrolizumab, and ipilimumab, as well as the pros and cons of using their blockers in relapse control after HSCT. In conclusion, it seems that CI therapy seems effective for this population. Future investigations may provide detailed outlook of this curative options.
Keyphrases
- free survival
- dna damage
- acute myeloid leukemia
- cell cycle
- mental health
- current status
- angiotensin converting enzyme
- rectal cancer
- advanced non small cell lung cancer
- prognostic factors
- hematopoietic stem cell
- stem cells
- bone marrow
- mesenchymal stem cells
- cell therapy
- angiotensin ii
- epidermal growth factor receptor