Changes in Albuminuria But Not GFR are Associated with Early Changes in Kidney Structure in Type 2 Diabetes.
Helen C LookerMichael MauerPierre-Jean SaulnierJennifer L HarderViji NairCarine M Boustany-KariPaolo GuarnieriJon HillCordell A EsplinMatthias KretzlerRobert G NelsonBehzad NajafianPublished in: Journal of the American Society of Nephrology : JASN (2020)
In American Indians with type 2 diabetes and preserved GFR at baseline, increasing ACR reflects the progression of earlier structural glomerular lesions, whereas early GFR decline may not accurately reflect such lesions.