Diffusion-tensor magnetic resonance imaging captures increased skeletal muscle fibre diameters in Becker muscular dystrophy.
Donnie CameronTooba Abbassi-DaloiiLaura G M HeezenNienke M van de VeldeZaïda KoeksThom T J VeegerMelissa T HooijmansSalma El AbdellaouiSjoerd G van DuinenJan J G M VerschuurenMaaike van PuttenAnnemieke M Aartsma-RusVered RazPietro SpitaliErik H NiksHermien E KanPublished in: Journal of cachexia, sarcopenia and muscle (2023)
DT-MRI RPBM metrics agree with histology and can quantify changes in muscle fibre size that are associated with regeneration without the need for biopsies. They therefore show promise as imaging biomarkers for muscular dystrophies.
Keyphrases
- muscular dystrophy
- skeletal muscle
- magnetic resonance imaging
- contrast enhanced
- stem cells
- insulin resistance
- duchenne muscular dystrophy
- high resolution
- computed tomography
- diffusion weighted imaging
- resistance training
- big data
- magnetic resonance
- ultrasound guided
- photodynamic therapy
- deep learning
- artificial intelligence
- body composition
- fluorescence imaging