3D Microwell Platforms for Control of Single Cell 3D Geometry and Intracellular Organization.

Robin E WilsonAleksandra K DenisinAlexander R DunnBeth L Pruitt

Published in: Cellular and molecular bioengineering (2020)

Using our novel polyacrylamide platforms, we were able to decouple the effects of 3D confinement and adhesive environment, finding that both influenced actin and nuclear structure.

Keyphrases

single cell
rna seq
reactive oxygen species