Paper-based ratiometric fluorescent sensing platform based on mixed quantum dots for the detection of glucose in urine.
Keke SongChenying LiuGuangbin ChenWenhao ZhaoShufang TianQian ZhouPublished in: RSC advances (2024)
A paper-based ratiometric fluorescent sensing platform has been developed for glucose detection based on a dual-emission fluorescent probe consisting of carbon quantum dots (C QDs) and CdTe QDs. When the two kinds of QDs are mixed, the fluorescence of C QDs is reversibly quenched by CdTe QDs. However, in the presence of glucose, the fluorescence of CdTe QDs is quenched by H 2 O 2 catalyzed by glucose oxidase (GOx), which restores the fluorescence of C QDs. The proposed paper-based ratiometric fluorescent sensing platform exhibited good sensitivity and selectivity towards glucose. The working linear range was 0.1 mM to 50 mM with a limit of detection (LOD) of 0.026 mM. Additionally, the proposed paper-based sensor possesses viability for the determination of glucose in actual urine samples.
Keyphrases
- quantum dots
- energy transfer
- fluorescent probe
- sensitive detection
- living cells
- blood glucose
- loop mediated isothermal amplification
- single molecule
- high throughput
- type diabetes
- real time pcr
- adipose tissue
- metabolic syndrome
- blood pressure
- insulin resistance
- high resolution
- skeletal muscle
- mass spectrometry
- room temperature
- simultaneous determination
- solid phase extraction