Association of CYP1A1 rs1048943 variant with aggressive periodontitis and its interaction with hyperlipidemia on the periodontal status.

Xian'e WangWenjing Li Wenli SongLi XuLi ZhangXianghui FengRuifang Lu Huanxing Meng

Published in: Journal of periodontal research (2019)

The G allele of the CYP1A1 rs1048943 gene was associated with GAgP, periodontal status and platelet-related inflammation status in a Chinese population. Hyperlipidemia could modulate the effect of CYP1A1 rs1048943 on the periodontal status of GAgP.

Keyphrases

high fat diet
oxidative stress
type diabetes
gene expression
copy number
insulin resistance
skeletal muscle
high fat diet induced