Appropriateness of prescribing profiles and intake adherence to non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: analysis of a retrospective longitudinal study using real-world data from Northern Portugal (AF-React Study).
Susana Silva PintoTeresa S HenriquesAndreia Sofia Costa TeixeiraHugo MonteiroCarlos MartinsPublished in: BMJ open (2024)
Dabigatran had the lowest percentage of guideline-consistent doses. Patients younger than 75 years with GFR >60 mL/min had the highest percentage with an adequate GFR range, while other groups who require closer GFR monitoring had lower percentages within an adequate GFR range. Adherence to NOACs differed among different drugs, with greater adherence to treatment with edoxaban and less adherence to apixaban.
Keyphrases
- atrial fibrillation
- oral anticoagulants
- end stage renal disease
- venous thromboembolism
- ejection fraction
- primary care
- chronic kidney disease
- glycemic control
- newly diagnosed
- big data
- prognostic factors
- emergency department
- peritoneal dialysis
- machine learning
- weight loss
- skeletal muscle
- artificial intelligence
- insulin resistance
- deep learning
- combination therapy
- smoking cessation