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Ligature-induced periodontitis induces systemic inflammation but does not alter acute outcome after stroke in mice.

Conor O'BoyleMichael J HaleyEloïse LemarchandCraig J SmithStuart M AllanJoanne E KonkelCatherine B Lawrence
Published in: International journal of stroke : official journal of the International Stroke Society (2019)
Our data show that despite elevated systemic inflammation in periodontitis, oral inflammatory disease does not impact acute stroke pathology in terms of severity, determined primarily by infarct volume. This indicates that, at least in this experimental paradigm, periodontitis alone does not alter acute outcome after cerebral ischemia.
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