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Multifocal electroretinography increases following experimental glaucoma in nonhuman primates with retinal ganglion cell axotomy.

T Michael NorkCharlene B Y KimAlexander W KatzCarol A RasmussenMark BanghartJames N Ver Hoeve
Published in: Documenta ophthalmologica. Advances in ophthalmology (2023)
The RMS amplitudes of the short-latency mfERG K1 waveforms are not altered following axotomy but undergo marked increases following elevated IOP. This suggests that the increase in mfERG amplitude was not solely a result of RGC loss and may reflect photoreceptor and bipolar cell dysfunction and/or changes in Müller cells.
Keyphrases
  • single cell
  • cell therapy
  • induced apoptosis
  • oxidative stress
  • bipolar disorder
  • mesenchymal stem cells
  • signaling pathway
  • cell proliferation
  • optic nerve