Renoprotective effects of prazosin on ischemia-reperfusion injury in rats.

M M RahimiA BagheriY BagheriE FathiS BagheriA V NiaS JafariSoheila Montazersaheb

Published in: Human & experimental toxicology (2021)

These findings suggest that prazosin could be a good candidate to attenuate renal IR injury due to its ability to modulate renal function, apoptosis and inflammation.

Keyphrases

oxidative stress
endoplasmic reticulum stress
cell cycle arrest
cell death
diabetic nephropathy
signaling pathway