The influence of antibiotic administration on the outcomes of head-and-neck squamous cell carcinoma patients undergoing definitive (chemo)radiation.

Alexander RühleJiadai ZouMargaretha GlaserLennard HalleEleni GkikaHenning SchäferAndreas KnopfChristoph BeckerAnca-Ligia GrosuIlinca PoppNils H Nicolay

Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2023)

Peritherapeutic antibiotic usage was associated with impaired oncological outcomes in HNSCC patients undergoing (chemo)radiation. Further studies including microbiome analyses are required to elucidate underlying mechanisms.

Keyphrases

patients undergoing
locally advanced
photodynamic therapy
rectal cancer
cancer therapy
combination therapy
squamous cell carcinoma
radiation induced
prostate cancer
metabolic syndrome
insulin resistance
weight loss