The impact of elexacaftor/tezacaftor/ivacaftor on body composition in a small cohort of youth with cystic fibrosis.

Andrea GranadosChristine L ChanAmir MoheetTimothy VigersAna María ArbeláezKatie Larson Ode

Published in: Pediatric pulmonology (2023)

ETI resulted in increased weight and fat mass. BMI and muscle mass did not change. Both insulin secretion and insulin resistance increased. Longer-term metabolic consequences of ETI need further investigation.

Keyphrases

body composition
insulin resistance
resistance training
body mass index
adipose tissue
bone mineral density
physical activity
weight gain
cystic fibrosis
preterm infants
mental health
high fat diet
type diabetes
young adults
weight loss
polycystic ovary syndrome
skeletal muscle
gestational age
high fat diet induced