Longitudinal Hippocampal Diffusion-Weighted Imaging and T2 Relaxometry Demonstrate Regional Abnormalities Which Are Stable and Predict Subfield Pathology in Temporal Lobe Epilepsy.
Seyed Amir Ali AdelSarah TreitWasan Abd WahabGraham LittleLaura SchmittAlan H WilmanChristian BeaulieuDonald W GrossPublished in: Epilepsia open (2022)
Diffusion and T2 abnormalities in ipsilateral and contralateral hippocampi remained unchanged between the scans suggesting permanent micro-structural alterations. MD and T2 demonstrated good sensitivity and specificity to detect hippocampal subfield neuron loss on post-surgical histology, supporting the potential that high-resolution hippocampal DTI and T2 could be used to diagnose HS subtype before surgery.
Keyphrases
- temporal lobe epilepsy
- diffusion weighted imaging
- high resolution
- contrast enhanced
- cerebral ischemia
- magnetic resonance imaging
- coronary artery bypass
- molecular dynamics
- magnetic resonance
- coronary artery disease
- surgical site infection
- brain injury
- risk assessment
- subarachnoid hemorrhage
- acute coronary syndrome
- multiple sclerosis
- high speed
- atrial fibrillation
- blood brain barrier
- tandem mass spectrometry