Facial soft tissue volume decreases during metreleptin treatment in patients with partial and generalized lipodystrophy.
Konstanze MiehleMichael StumvollMathias FasshauerThomas HierlPublished in: Endocrine (2017)
Metreleptin replacement leads to loss of facial soft tissue volume in FPLD and generalized LD. However, volume changes in most patients are not visible by the naked eye.