Analysis of brain and spinal MRI measures in a common domain to investigate directional neurodegeneration in motor neuron disease.

C TohA KeslakeT PayneA OnwuegbuzieJ HardingK BasterN HoggardP J ShawI D WilkinsonThomas M Jenkins

Published in: Journal of neurology (2022)

Analysis of brain and cervical spinal MRI data in a common domain enabled investigation of pathophysiological hypotheses in vivo. A cranio-caudal step-change in MND patients was observed, and requires further investigation in larger cohorts.

Keyphrases

end stage renal disease
spinal cord
magnetic resonance imaging
contrast enhanced
white matter
resting state
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
big data
machine learning
patient reported outcomes
blood brain barrier
artificial intelligence
deep learning