Cephaeline is an inductor of histone H3 acetylation and inhibitor of mucoepidermoid carcinoma cancer stem cells.
Luan César da SilvaGabriell Bonifácio BorgatoVivian Petersen WagnerManoela Domingues MartinsGuilherme Zweig RochaMárcio Ajudarte LopesAlan Roger Dos Santos SilvaGilberto de Castro JuniorLuiz Paulo KowalskiJacques Eduardo NörCristiane Helena SquarizeRogerio de Moraes CastilhoPablo Agustin VargasPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2021)
Cephaeline has shown anti-cancer properties in all MEC cell lines tested by regulating tumor cells' viability, migration, proliferation, and disrupting the ability of cancer cells to generate tumorspheres.