Classifying glioma via liquid biopsy--progress towards an unmet clinical need.

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)

The diagnosis and classification of glioma by liquid biopsy represents a critical unmet need in neuro oncology. A recent study demonstrates targeted next generation sequencing (NGS) of cell-free DNA (cfDNA) from cerebrospinal fluid (CSF) as an evolving option for liquid biopsy in patients with glioma.

Keyphrases

cerebrospinal fluid
ultrasound guided
fine needle aspiration
ionic liquid
machine learning
palliative care
deep learning
copy number
cancer therapy
dna methylation
genome wide