Preparation, in vitro and in vivo evaluation of pinocembrin-loaded TPGS modified liposomes with enhanced bioavailability and antihyperglycemic activity.

Xinyi ShenWanjing RongMichael Adu-FrimpongQing HeXiaoxiao LiFeng ShiHao JiElmurat ToreniyazovXiaoli XiaJian ZhangQilong WangJiangnan YuXi-Ming Xu

Published in: Drug development and industrial pharmacy (2022)

These results show PCBT-liposomal preparation as an excellent nano-carrier which has the potential to improve water solubility, bioavailability, and antihyperglycemic activity of PCB, amid broadening the application of PCB in the clinical settings.

Keyphrases

drug delivery
molecularly imprinted
risk assessment
drug release
climate change
mass spectrometry
solid phase extraction