Vogt-Koyanagi-Harada disease with a unilateral presentation in a patient with marijuana overuse: Role of multimodal imaging in suspected patients.
Seyedeh Maryam HosseiniAhmad GharouniMehrdad Motamed ShariatiPublished in: Clinical case reports (2023)
To report a patient addicted to marijuana with the diagnosis of Vogt-Koyanagi-Harada (VKH) disease with a unilateral presentation. A 24-year-old man presented to us with painless decreased vision in his right eye (RE) and photophobia 3 days ago. No history of significant family or past medical history was documented. Spectral-domain optical coherence tomography (SD-OCT) of the RE showed multiple areas of subretinal fluid in the macula. Indocyanine green angiography (ICGA) revealed round hypocyanescent dark dots (HDD) of similar size, evenly distributed in both eyes. With the diagnosis of VKH disease, anti-inflammatory treatment was started. To our knowledge, this is the first reported case of suspected VKH in a patient with marijuana overuse. Regarding the complex effects of tetrahydrocannabinol (THC), the active ingredient of marijuana, on the vascular and immune systems, reaching a definite conclusion is not possible. This report shows the value of multimodal imaging in patients with unusual presentations.
Keyphrases
- optical coherence tomography
- case report
- diabetic retinopathy
- high resolution
- healthcare
- anti inflammatory
- pulmonary embolism
- optic nerve
- ejection fraction
- computed tomography
- single cell
- prognostic factors
- photodynamic therapy
- fluorescent probe
- chronic kidney disease
- patient reported outcomes
- fluorescence imaging
- smoking cessation
- simultaneous determination
- mass spectrometry
- neural network