Characteristics and Predictors of Apparent Treatment Resistant Hypertension in Real-World Populations Using Electronic Health Record-Based Data.
Eissa JafariRhonda M Cooper-DeHoffMark B EffronWilliam R HoganCaitrin W McDonoughPublished in: medRxiv : the preprint server for health sciences (2023)
Large, diverse real-world populations showed a similar prevalence of aTRH, 16.7% in OneFlorida and 11.3% in REACHnet, compared to those observed from other cohorts.Patients classified as apparent treatment resistant hypertension were significantly older and had a higher prevalence of comorbid conditions such as diabetes, dyslipidemia, coronary artery disease, heart failure with preserved ejection fraction, and chronic kidney disease stages 1-3.Within diverse, real-world populations, the strongest predictors for apparent treatment resistant hypertension were black race, higher body mass index, heart failure, chronic kidney disease, and diabetes.
Keyphrases
- end stage renal disease
- chronic kidney disease
- electronic health record
- blood pressure
- peritoneal dialysis
- heart failure
- body mass index
- coronary artery disease
- type diabetes
- risk factors
- cardiovascular disease
- diffusion weighted imaging
- clinical decision support
- ejection fraction
- glycemic control
- physical activity
- newly diagnosed
- percutaneous coronary intervention
- adverse drug
- genetic diversity
- metabolic syndrome
- community dwelling
- weight gain
- patient reported outcomes
- atrial fibrillation
- magnetic resonance
- computed tomography
- aortic stenosis
- acute heart failure