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Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains.

Daniel W RennerLance ParsonsJacob T ShreveEsteban A EngelChad V KunyLynn EnquistDonna NeumannColleen MangoldMoriah L Szpara
Published in: Microbiology resource announcements (2021)
Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.
Keyphrases
  • herpes simplex virus
  • genome wide
  • escherichia coli
  • dna methylation
  • copy number
  • genetic diversity