Benign tumors in myotonic dystrophy type I target disease-related cancer sites.
Rotana AlsaggafDiane Marie M St GeorgeMin ZhanRuth M PfeifferYoujin WangLesley A AndersonZhiwei LiuJill KoshiolAndrew J BauerKathryn R WagnerMark H GreeneSania AmrShahinaz M GadallaPublished in: Annals of clinical and translational neurology (2019)
Our study showed a similar site-specific benign tumor profile to that previously reported for DM1-associated cancers. The possible association between benign tumors and subsequent cancer in classic DM1 patients warrants further investigation as it may guide identifying patients at elevated risk of cancer. Our findings underscore the importance of following population-based screening recommendations in DM1 patients, for example, for colorectal cancer.