Long noncoding RNA Pvt1 regulates the immunosuppression activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice.

Yu ZhengXinyu TianTingting WangXueli XiaFenghua CaoJie TianPing XuJie MaHuaxi XuShengjun Wang

Published in: Molecular cancer (2019)

Taken together, our results demonstrate a critical role for lncRNA Pvt1 in regulating the immunosuppression activity of G-MDSCs, and lncRNA Pvt1 might thus be a potential antitumor immunotherapy target.

Keyphrases

long noncoding rna
induced apoptosis
cell cycle arrest
long non coding rna
cell death
metabolic syndrome
human health
skeletal muscle
endoplasmic reticulum stress
wild type