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Intraepidermal Merkel cell carcinoma: A case series of a rare entity with clinical follow up.

George JourPhyu P AungEduardo Rozas-MuñozJohnathan L CurryVictor PrietoDoina Ivan
Published in: Journal of cutaneous pathology (2017)
Our findings raise the awareness that MCC strictly in situ does exist and it should be included in the differential diagnosis of Paget's or extramammary Paget's disease, pagetoid squamous cell carcinoma, melanoma and other neoplasms that typically show histologically pagetoid extension of neoplastic cells. Considering the limited number of cases reported to date, the diagnosis of isolated MCCIS should not warrant a change in management from the typical MCC.
Keyphrases
  • squamous cell carcinoma
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • lymph node metastasis
  • radiation therapy
  • skin cancer