A randomized, placebo-controlled trial of beloranib for the treatment of hypothalamic injury-associated obesity.

Ashley H ShoemakerJoseph ProiettoM Jennifer AbuzzahabTania MarkovicJaret MalloyDennis D Kim

Published in: Diabetes, obesity & metabolism (2017)

Beloranib treatment resulted in progressive weight loss in patients with HIAO that was comparable to that observed with beloranib in patients with exogenous obesity. These findings indicate a novel mechanism for treating obesity in patients with HIAO.

Keyphrases

weight loss
insulin resistance
metabolic syndrome
bariatric surgery
type diabetes
weight gain
high fat diet induced
roux en y gastric bypass
multiple sclerosis
gastric bypass