Enpp1 deficiency caused chondrocyte apoptosis by inhibiting AMPK signaling pathway.
Zhiqiang GaoQiang WangKai GuoXinhua LiYu-Feng HuangPublished in: Journal of orthopaedic surgery and research (2023)
Consequently, Enpp1 deficiency plays an essential role in knee OA by regulating AMPK signaling pathway.