Appropriate endpoints for evaluation of new antibiotic therapies for severe infections: a perspective from COMBACTE's STAT-Net.

Jean-François TimsitMarlieke E A de KrakerHarriet SommerEmmanuel WeissEsther BettiolMartin WolkewitzStavros NikolakopoulosDavid WilsonStephan Harbarthnull null

Published in: Intensive care medicine (2017)

Regulatory authorities, pharmaceutical companies, and clinicians need to agree on the most appropriate clinical endpoints for severe infections to ensure efficient approval of new, effective antibiotic agents.

Keyphrases

early onset
palliative care
cell proliferation
transcription factor