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Diagnostic Pitfall and Clinical Characteristics of Variant Versus Wild-Type Transthyretin Amyloid Cardiomyopathy in Asian Population: The Korean Nationwide Cohort Study.

Darea KimJong-Chan YounHye Won LeeJaewon OhJung Woo SonHyun-Jai ChoSeul LeeNishant R ShahMichelle M KittlesonEun-Seok Jeon
Published in: Journal of Korean medical science (2024)
A nationwide cohort of ATTR-CM exhibited less male predominance, a proportion of patients without increased LV wall thickness, and distinct characteristics of genetic mutations, compared to cohorts in other parts of the world. Our results highlight the ethnic variation in ATTR-CM and may contribute to improving the screening process for ATTR-CM in the Asian population.
Keyphrases
  • wild type
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • heart failure
  • peritoneal dialysis
  • prognostic factors
  • genome wide
  • gene expression
  • dna methylation
  • atrial fibrillation