Variation of platelet function in clinical phenotypes of acute venous thromboembolism - Results from the GMP-VTE project.
Marina Panova-NoevaBianca WagnerMarkus NaglerThomas KoeckVincent Ten CateLisa EggebrechtJürgen H ProchaskaImke MeyerChristoph GerdesHenri M H SpronkKarl J LacknerHugo Ten CateKirsten LeineweberStefan HeitmeierStavros V KonstantinidesPhilipp S WildPublished in: Journal of thrombosis and haemostasis : JTH (2021)
This explorative study suggests an important distinction between PE-related phenotypes and iDVT when considering clinical and platelet function data. Lower platelet-dependent TG along with reduced platelet reactivity suggest higher platelet degranulation in PE-dependent phenotypes compared to iDVT.