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Treatment of orbital lymphatic malformation with oral sirolimus: a case report.

Carmen Alba LineroMaría García LorenteAnil Rahul RachwaniGuillermo Luque-ArandaMaría-Isabel Pérez-CabezaJulia Escudero Gómez
Published in: Arquivos brasileiros de oftalmologia (2022)
It is estimated that lymphatic malformations in children account for 6% of all benign vascular malformations. New medical therapies have been developed for the management of lymphatic orbital disease. The purpose of this article was to describe a clinical case of orbital venolymphatic malformation in a 10-year-old boy, causing proptosis and palpebral edema. The lesion was initially treated with local sclerotherapy. However, the lesion relapsed, and was successfully treated with oral sirolimus. Prospective studies are warranted to determine the appropriate dose and extend the indications of sirolimus in these patients.
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