Effect of Azelaic Acid on Psoriasis Progression Investigated Based on Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (AKT) Signaling Pathway.
Licui LiHuixiu LuYanli ZhangQian LiShaomin ShiYaling LiuPublished in: Clinical, cosmetic and investigational dermatology (2022)
Azelaic acid may inhibit the activation of PI3K/AKT signaling pathway and angiogenesis, thereby improving the symptoms of psoriasis.
Keyphrases
- signaling pathway
- pi k akt
- protein kinase
- cell proliferation
- cell cycle arrest
- induced apoptosis
- epithelial mesenchymal transition
- endothelial cells
- vascular endothelial growth factor
- atopic dermatitis
- atomic force microscopy
- high resolution
- depressive symptoms
- oxidative stress
- cell death
- high speed
- single molecule