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Data-Driven Characterization of Genetic Variability in Disease Pathways and Pesticide-Induced Nervous System Disease in the United States Population.

Marissa B KosnikPhilipp AntczakPeter Fantke
Published in: Environmental health perspectives (2024)
Our findings support that pesticides contribute to nervous system disease, and we developed priority lists of SNPs, pesticides, and pathways for further study. This data-driven approach can be adapted to other chemicals, diseases, and locations to characterize differential population susceptibility to chemical exposures. https://doi.org/10.1289/EHP14108.
Keyphrases
  • risk assessment
  • genome wide
  • air pollution
  • gene expression
  • gas chromatography
  • endothelial cells
  • genome wide association