Innovative Drug Discovery: Targeting Cancer, Neurological Disorders, and Obesity.
Robert B KargboPublished in: ACS medicinal chemistry letters (2024)
The landscape of therapeutic innovation is rapidly evolving, with significant advances in cancer treatment, obesity management, and the modulation of protein interactions in neurodegenerative disorders. This Patent Highlight explores the scientific breakthroughs described in four recent patents covering novel therapeutic compounds, advanced methods for identifying E3 ligase substrates, and developing new strategies for combating obesity and its related metabolic disorders. These innovations, focusing on specific molecular targets and pathways, promise more effective and personalized treatment options, addressing unmet needs in oncology, neurology, and metabolic health.
Keyphrases
- insulin resistance
- metabolic syndrome
- weight loss
- drug discovery
- type diabetes
- high fat diet induced
- weight gain
- healthcare
- public health
- papillary thyroid
- palliative care
- mental health
- body mass index
- adipose tissue
- machine learning
- cancer therapy
- small molecule
- protein protein
- single molecule
- blood brain barrier
- big data
- social media
- amino acid
- subarachnoid hemorrhage
- deep learning
- drug delivery
- brain injury