Anisodamine Hydrobromide Protects Glycocalyx and Against the Lipopolysaccharide-Induced Increases in Microvascular Endothelial Layer Permeability and Nitric Oxide Production.

Xiaoqiang DuHuan LiuYonghua YueQingjiang WuWenli JiangYan QiuYe Zeng

Published in: Cardiovascular engineering and technology (2020)

Ani HBr protects ECs against LPS-induced increase in cell barrier permeability and nitric oxide production via preserving the integrity of glycocalyx. Ani HBr is a promising drug to rescue or protect the glycocalyx.

Keyphrases

lipopolysaccharide induced
inflammatory response
nitric oxide
lps induced
endothelial cells
nitric oxide synthase
hydrogen peroxide
single cell
cell therapy
stem cells
emergency department
bone marrow
adverse drug
drug induced