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Specific detection of high mobility group box 1 degradation product with a novel ELISA.

Takaaki TotokiTakashi ItoShingo YamadaGoichi HondaTsuyoshi HattoriIkuro Maruyama
Published in: Molecular medicine (Cambridge, Mass.) (2021)
In this study, we obtained a desHMGB1-specific monoclonal antibody. ELISA using the novel monoclonal antibody may be an option for the in-depth analysis of HMGB1-induced pathogenicity as well as rTM-mediated therapeutic efficiency.
Keyphrases
  • monoclonal antibody
  • high glucose
  • transcription factor
  • diabetic rats
  • loop mediated isothermal amplification
  • binding protein
  • oxidative stress
  • biofilm formation
  • endothelial cells
  • real time pcr
  • stress induced