Repeated Stereotactic Radiotherapy for Local Brain Metastases Failure or Distant Brain Recurrent: A Retrospective Study of 184 Patients.
Laure KuntzClara Le FèvreDelphine JarnetAudrey KellerPhilippe MeyerChristophe MazzaraHélène CebulaGeorges NoëlDelphine AntoniPublished in: Cancers (2023)
Lung cancer and melanoma were associated with a lower NDFS compared to breast cancer. A low KPS, a low number of SRT sessions, synchronous extracerebral metastases, synchronous BMs, extracerebral progression at SRT1, a high BMV grade, no WBRT and local recurrence were also associated with a lower NDFS. A high KPS at SRT1 and low BMV grade are prognostic factors for better OS, regardless of the number of BM recurrence events.
Keyphrases
- prognostic factors
- brain metastases
- small cell lung cancer
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- ejection fraction
- early stage
- lymph node
- peritoneal dialysis
- radiation therapy
- free survival
- resting state
- locally advanced
- squamous cell carcinoma
- functional connectivity
- radiation induced
- multiple sclerosis
- rectal cancer