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Advanced Bio-Based Polymers for Astrocyte Cell Models.

Lidija GradišnikRoman BošnjakTina MaverTomaž Velnar
Published in: Materials (Basel, Switzerland) (2021)
The development of in vitro neural tissue analogs is of great interest for many biomedical engineering applications, including the tissue engineering of neural interfaces, treatment of neurodegenerative diseases, and in vitro evaluation of cell-material interactions. Since astrocytes play a crucial role in the regenerative processes of the central nervous system, the development of biomaterials that interact favorably with astrocytes is of great research interest. The sources of human astrocytes, suitable natural biomaterials, guidance scaffolds, and ligand patterned surfaces are discussed in the article. New findings in this field are essential for the future treatment of spinal cord and brain injuries.
Keyphrases
  • tissue engineering
  • spinal cord
  • cell therapy
  • single cell
  • endothelial cells
  • stem cells
  • spinal cord injury
  • escherichia coli
  • mesenchymal stem cells
  • combination therapy
  • neuropathic pain
  • bone marrow