The PRIAMO study: urinary dysfunction as a marker of disease progression in early Parkinson's disease.
Marina PicilloR PalladinoP BaroneR ErroC ColosimoR MarconiL MorganteA Antonininull nullPublished in: European journal of neurology (2017)
This is the first prospective longitudinal study involving a large cohort of PD patients demonstrating the relevance of urinary dysfunction as an early marker of higher motor and non-motor disability as well as lower health-related quality of life. These findings support a role for urinary dysfunction as an early marker of more severe disease progression.